罗哌卡因配伍芬太尼用于硬膜外镇痛分娩的临床观察

目的：探讨罗哌卡因联合芬太尼在硬膜外镇痛分娩中的作用。方法选择在本院行硬膜外镇痛分娩的产妇80例，随机分为罗哌卡因联合芬太尼镇痛组（观察组， n=40）与罗哌卡因联合吗啡镇痛组（对照组， n=40），观察并比较两组的术后24 h、48 h静息、活动、咳嗽时的VAS评分及临床效果。结果观察组术后24 h、48 h静息、活动、咳嗽时的VAS评分均明显低于对照组（P〈0.05）；临床镇痛效果明显优于对照组（P〈0.05）。观察组皮肤瘙痒1例，恶心呕吐1例，无终止用药病例；对照组皮肤瘙痒10例，恶心呕吐9例，终止用药1例。结论罗哌卡因与芬太尼配伍在硬膜外镇痛分娩中应用，可提高镇痛效果，降低不良反应发生率，且产妇心血管在用药后有较好的稳定性。

Clinical observation of ropivacaine with fentanyl for epidural analgesia in childbirth

Objective To investigate the role of ropivacaine with fentanyl for epidural analgesia in childbirth. Methods 80 cases birth mothers,of epidural analgesia in our hospital were randomly divided into ropivacaine with fentanyl analgesia group （observate group, n=40） and ropivacaine plus morphine analgesia group （control group, n=40）, the two groups were observed the VAS scores of resting, activity, coughing after 24 h/48 h ,and compared the clinical effect. Results The VAS scores of resting, activity, coughing after 24 h/48 h in observation group were significantly lower than those in control group （P〈0.05）;and the clinical analgesic effect than the control group （P〈0.05）.The observe group had one case of pruritus, one case of nausea and vomiting, no termination of drug cases;in the control group 10 cases of pruritus, nine cases of nausea and vomiting, one case of termination of medication. Conclusion Ropivacaine and fentanyl epidural analgesia in childbirth can improve analgesia and reduce the incidence of adverse reactions, and stabie the maternal’s cardiovascular after treatment.