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Incidence of steroid-associated osteonecrosis of the talus: a prospective MRI study |
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| Authors: | Tomonori Shigemura Junichi Nakamura Yoshitada Harada Masaaki Sakamoto Kazuhisa Takahashi Shunji Kishida |
| Affiliation: | 1. Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba City, Chiba, 260-8670, Japan 2. Department of Orthopaedic Surgery, Chibaken Saiseikai Narashino Hospital, 1-1-1 Izumi-cho, Narashino City, Chiba, 275-8580, Japan 3. Department of Orthopaedic Surgery, Chiba Kaihin Municipal Hospital, 3-31-1 Isobe, Mihama-ku, Chiba City, Chiba, 261-0012, Japan |
| Abstract: | ObjectiveThe purpose of this study was to determine the incidence of steroid-associated osteonecrosis (ON) of the talus in systemic lupus erythematosus (SLE) patients using a prospective magnetic resonance imaging (MRI) study.MethodsWe prospectively evaluated 110 SLE patients (220 tali) who required corticosteroid therapy using MRI. The incidence of ON of the talus was compared with the incidence of ON of the femoral head. We also divided these patients into two groups: those with and without ON of the talus. We compared these groups for gender differences, ages at initial corticosteroid therapy, and highest daily corticosteroid dosages.ResultsThe incidence of ON of the talus was significantly lower than the incidence of ON of the femoral head (7.3 versus 49.5 %; p?Conclusion Our results revealed that the incidence of ON of the talus was significantly lower than the incidence of ON of the femoral head. |
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