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胺碘酮联合贝那普利治疗阵发性心房颤动70例临床分析
引用本文:杜文惠,彭风芹,王平,谢素屏,刘玉锐,王继红,杨永进,樊向明,郝鸿博.胺碘酮联合贝那普利治疗阵发性心房颤动70例临床分析[J].中国临床实用医学,2010,4(9):112-113.
作者姓名:杜文惠  彭风芹  王平  谢素屏  刘玉锐  王继红  杨永进  樊向明  郝鸿博
作者单位:冀中能源峰峰集团邯郸医院内科,056002
摘    要:目的观察胺碘酮联合贝那普利对阵发性房颤的疗效。方法选择我院2008年3月至2010年3月期间阵发性心房纤颤患者145例,随机分为治疗组(胺碘酮+贝那普利)和对照组(单用胺碘酮),对照组应用胺碘酮治疗,治疗组在此基础加用贝那普利。结果随访12个月,治疗组窦性心律维持率明显高于对照组(P〈0.05),左房内径亦有显著性缩小(P〈0.05)。结论贝那普利具有抑制心房电重构和解剖重构,降低房颤复发率及阻止房颤持续的作用,胺碘酮联合贝那普利能更有效地治疗和预防阵发性房颤。

关 键 词:阵发性房颤  贝那普利  胺碘酮

Clinical analysis of 70 cases of Amiodarone combined with Benazepril on treatment in paroxysmal atrial fibrillation patient
Institution:DU Wen-hui,PENG Feng-qin, WANG Ping, et al. (Jizhong Energy Fengfeng group Handan Hospital, Handan , Hebei 056002, China)
Abstract:Objective To observe the effect of Amiodarone combined with Benazepril treating paroxysmal atrial fibrillation.Methods 145 Paroxysmal atrial fibrillation patients were enrolled and randomly divided into treatment group and control group.The treatment group were treated with Amiodarone and Benazepril,and the control group only with Amiodarone.All the patients have been observed for 12 months.Results The sinus rhythm maintenace rate in treatment group is higher than control group and the left ateial diameter decreased remarkably in treated group than that in control group (P < 0.05).Conclusion Benazepril can inhibit electronic and anatomical remodeling of atrial,and can reduce the recurrence rate of atrial fibrillation,and prevent persistence of atrial fibrillation.So Amiodarone combined with Benazepril can more effectively to treat and prevent the patients with paroxysmal atrial fibrillation
Keywords:Paroxysmal atrial fibrillation  Benazepril  Amiodarone
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