早期营养干预对头颈部肿瘤同期放化疗患者营养状况及耐受性的影响

目的 探讨早期营养干预对头颈部肿瘤患者营养状况及放化疗耐受性的影响.方法 将70例头颈部肿瘤患者随机分为观察组和对照组,对照组接受常规护理,观察组在对照组基础上增加早期营养干预,分别评估两组患者的营养监测指标的变化、观察治疗耐受性情况.结果 观察组放疗结束的各项营养指标下降明显小于对照组.两组患者放疗和化疗按预期的时间和剂量完成情况及因毒副反应中断治疗天数比较,差异有统计学意义（P＜0.05）.结论 早期营养干预可有效地改善营养状态,提高头颈部肿瘤患者放化疗耐受性,促进康复.

The impact of early nutritional intervention on nutritional status and treatment tolerance in head and neck cancer patients undergoing concurrent chemoradiotherapy

Objective To investigate the impact of an early nutritional intervention on nutritional status and treatment tolerance in patients undergoing chemoradiotherapy for head and neck cancer（HNC）. Methods Seventy patients under- going chemoradiotherapy were randomly divided into two groups, the experimental group and the control group. In ex- perimental group patients were administered for early nutritional intervention, whereas patients in control group re- ceived routine care. The nutritional status, treatment tolerance, patients who completed the planned chemoradiotherapy were compared between two groups. Results Compared with the control group, the experimental patients nutritional sta- tus at the end of treatment was less than the control group （P〈0.05）. Moreover, two groups patients all completed the planned ehemoradiotherapy, and they experienced fewer radiotherapy breaks for toxicity （P〈0.05）. Conclusion Early nutritional intervention in patients with HNC receiving chemoradiotherapy can effectively improve nutritional status, treatment tolerance and promote cancer rehabilitation.