医用几丁糖预防剖宫产术后粘连的疗效观察

目的 探讨医用几丁糖预防剖宫产术后粘连的疗效.方法 以2005年1月～2013年6月收治的二次剖宫产产妇为样本库,治疗组（使用医用几丁糖）102例,对照组（未使用医用几丁糖）100例.观察两组患者第二次剖宫产术时的盆腹腔粘连情况及第一次剖宫产术后排气时间、腹痛情况、术后病率、出血量及切口愈合情况.结果 两组患者盆腹腔粘连情况：治疗组预防粘连有效率达78.4％;而对照组50.0％,差异有统计学意义（x2=17.79,P＜0.01）.治疗组的排气时间、腹痛情况与对照组比较,差异有统计学意义（P＜0.01）.两组术后病率、出血量及切口愈合情况比较,差异无统计学意义（P＞0.05）.结论 几丁糖预防剖宫产手术后粘连效果显著,同时可缓解疼痛促进术后早排气.

Curative effects of medical chitosan in the prevention of adhesion after caesarean section

Objective To explore the curative effects of medical chitosan in the prevention of adhesion after caesarean section. Methods The parturients who were admitted to our hospital from January 2005 to June 2013 and received re- peated caesarean section were selected as samples. 102 parturients were assigned into treatment group （with the use of medical chitosan）, and 100 parturients were assigned into control group （without the use of medical chitosan）. The con- ditions of pelvic and abdominal adhesion of the two groups during the repeated caesarean section were observed. The intestinal exhaust time, conditions of abdominal pain, postoperative morbidity, amount of bleeding and incision condi- tions after the first caesarean section were also observed. Results The conditions of pelvic and abdominal adhesion of the two groups showed that the effective rate of adhesion prevention in treatment group was 78.4%, while that in control group was only 50.0%. The difference of the two groups was statistically significant （x2=lT.79,P〈0.01）. The differences of intestinal exhaust time and conditions of abdominal pain between the two groups were statistically significant （P〈 0.01）. The differences of postoperative morbidity, amount of bleeding and incision conditions between the two groups were not statistically significant（P〉0.05）. Conclusion Chitosan in the prevention of adhesion after caesarean section are significantly effective, which also helps alleviate pain and promote postoperative intestinal exhaust.