| 依诺肝素与普通肝素联合重组组织纤溶酶原激活剂溶栓治疗ST段抬高的急性心肌梗死的研究 |
| |
| 引用本文： | 蒋建东,蒋超旦,杨松.依诺肝素与普通肝素联合重组组织纤溶酶原激活剂溶栓治疗ST段抬高的急性心肌梗死的研究[J].现代中西医结合杂志,2010,19(29). |
| |
| 作者姓名： | 蒋建东 蒋超旦 杨松 |
| |
| 作者单位： | 江苏大学附属宜兴医院,江苏,宜兴,214200 |
| |
| 摘 要： | 目的比较依诺肝素与普通肝素在ST段抬高的急性心肌梗死(STEMI)重组组织纤溶酶原激活剂(rt-PA)溶栓时应用的疗效及安全性。方法 91例STEMI患者随机分成2组:治疗组46例予rt-PA溶栓联合依诺肝素,对照组45例予rt-PA溶栓联合普通肝素。观察溶栓开始后60 min及120 min梗死相关血管再通率、治疗中出血并发症及30 d左心室射血分数(LVEF)。结果溶栓开始后60 min治疗组血管再通率显著高于对照组,溶栓开始后90 min治疗组与对照组的血管再通率比较无显著性差异。治疗组与对照组30 d内梗死后心绞痛、再梗死、死亡率、中风、需要血运重建无显著性差异。治疗组30 d LVEF显著高于对照组。出血发生率治疗组与对照组比较无显著性差异。结论与普通肝素比较,依诺肝素联合rt-PA静脉溶栓治疗STEMI患者安全有效,能更早开通梗死相关血管,改善左心室功能,不增加出血并发症。
|
| 关 键 词： | ST段抬高 急性心肌梗死 血栓溶解疗法 依诺肝素 组织纤溶酶原激活剂 |
Study of enoxaparin and general heparin combined with recombinant tissue plasminogen activators thrombolysis on acute myocardial infarction patients with ST segment elevation |
| |
| Jiang Jiandong,Jiang Chaodan,Yang Song.Study of enoxaparin and general heparin combined with recombinant tissue plasminogen activators thrombolysis on acute myocardial infarction patients with ST segment elevation[J].Modern Journal of Integrated Chinese Traditional and Western Medicine,2010,19(29). |
| |
| Authors: | Jiang Jiandong Jiang Chaodan Yang Song |
| |
| Institution: | Jiang Jiandong,Jiang Chaodan,Yang Song(The Affiliated Yixing Hospital of Jiangsu University,Yixing 214200,Jiangsu,China) |
| |
| Abstract: | Objective It is to compare the curative effect and safety of enoxaparin and general heparin combined with recombinant tissue plasminogen activators(rt-PA) thrombolysis on acute myocardial infarction patients with ST segment elevation(STEMI).Methods 91 STEMI patients were randomly divided into two groups.46 cases were in treatment group and treated with rt-PA thrombolysis combined with enoxaparin.The other 45 cases were in control group and treated with rt-PA thrombolysis combined with general heparin.The in... |
| |
| Keywords: | ST segment elevation acute myocardial infarction thrombolysis therapy enoxaparin tissue plasminogen activators |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
