儿童感染幽门螺杆菌对微量元素影响的探讨

目的通过了解儿童感染幽门螺杆菌后其微量元素水平的变化,为临床合理补充微量元素提供科学依据。方法检测400例儿童血清中幽门螺杆菌IgG抗体和IgM抗体,同时应用原子吸收光谱法测量其全血微量元素锌、铁、钙、铜、镁的含量。结果小儿Hp现症感染率为10.5%,既往感染率为2.0%。Hp感染组儿童全血中铁的水平明显低于未感染组（P〈0.05）,而且感染组的铁缺乏率高于未感染组（P〈0.05）,而锌、钙、镁、铜水平以及缺乏率在两组之间差异无统计学意义（P〉0.05）。结论 Hp感染是造成或加重儿童铁缺乏的重要因素;对Hp感染患儿应进行铁元素含量检测,必要时给予补铁治疗,以减少由此引起的铁缺乏对儿童生长发育的影响。

Study on Impact of Helicobacter pylori Infection on Trace Elements in Children

Objective To study the changes of the levels of trace elements in children with Helicobacter pylori(Hp) infection,and to provide a scientific basis for reasonably adding trace elements in clinical practice.Methods The levels of IgG and IgM antibodies of Hp in the sera of 400 children were detected;meanwhile,atomic absorption spectrometer was used to determine the contents of trace elements(zinc,iron,calcium,copper,and magnesium) in whole blood.Results The current infection rate of Hp in the children was 10.5%,and the past infection rate of Hp was 2.0%.There were statistically significant differences in the levels of iron between the patients and the healthy children(P<0.05).There were statistically significant differences in the rate of iron deficiency between the patients and the healthy children(P<0.05).No statistically significant difference was found in the levels and deficiency rates of zinc,calcium,magnesium,and copper between the patients and the healthy children(P>0.05).Conclusions The infection of Hp is an important factor for inducing or aggravating iron deficiency in children.The children with Hp infection should be detected the level of iron.It is helpful to prevent the iron deficiency in children if they are treated by adding iron in necessary time.