多囊卵巢综合征患者内分泌代谢特征分析及其临床危害的预防

目的分析多囊卵巢综合征患者内分泌代谢特征,为临床实施有效的预防措施提供参考信息。方法选择保定市三丰医院2006年1月-2009年12月收治的多囊卵巢综合征患者60例,其中肥胖型32例、非肥胖型28例,并以同期健康体检者60例作为对照组,分析两组的内分泌代谢特征并观察多囊卵巢综合征患者的并发症发生情况。结果观察组患者血清黄体生成素（LH）、雄激素（T）、胰岛素（INS）、催乳素（PRL）、总胆固醇（TC）、甘油三酯（TG）水平明显高于对照组,与对照组比较,差异均有统计学意义（P〈0.05）,且肥胖型患者更为严重;肥胖型多囊卵巢综合征患者高胰岛素血症、糖尿病发生率更高（P〈0.05）。结论多囊卵巢综合征患者内分泌代谢紊乱,且以肥胖型患者更为严重,临床上应针对性采取相应的预防措施,防止并发症的发生,降低临床危害。

Analysis on Endocrine Metabolism Characteristic of Patients with Polycystic Ovary Syndrome and Its Clinical Risk Prevention

Objective To analyze the endocrine metabolism characteristic of patients with polycystic ovary syndrome,and to provide the reference information for the clinical implementation of effective prevention measures. Methods Sixty patients with polycystic ovary syndrome hospitalized in Sanfeng Hospital of Baoding from January 2006 to December 2009 were selected as the observation group,including 32 cases of non-obese type and 28 cases of obese type.And 60 health examinees in the same period were served as the control group.The endocrine metabolism characteristics of the two groups were analyzed and the incidence of complications in patients with polycystic ovary syndrome was observed. Results The serum luteinizing hormone(LH),testosterone(T),insulin (INS),prolactin(PRL),total cholesterol(TC),and triglyceride(TG) levels of the observation group were significantly higher than those of the control group,and the difference was statistically significant(P<0.05).The incidence rates of hyperinsulinemia and diabetes in obese women with polycystic ovary syndrome were higher(P<0.05). Conclusions Endocrine metabolic disturbance is found in patients with polycystic ovary syndrome,moreover,it is more severe in obese patients.Clinical practice should be targeted to take appropriate preventive measures to prevent complications and reduce clinical risk.