湘南地区妇女子宫颈人乳头状瘤病毒感染的流行病学调查

目的统计了解本地区HPV感染基本情况,并探讨研究妇女子宫颈人乳头状瘤病毒（HPV）感染和女人生理期变化、性行为、生活习惯等因素的相关性。方法以2009年1月-2010年10月郴州市第一人民医院门诊接受妇科检查的女性1 108例为研究对象,对其阴道宫颈分泌物标本,进行21种HPV基因型的分型检测,同时调查其年龄、文化程度、职业、户籍、绝经、初次性生活年龄、性伴侣数、妊娠次数、初次妊娠年龄、流产、分娩次数、避孕方式、吸烟、饮酒等相关因素,最后用软件SPSS13.0进行卡方检验各危险因素的显著性。结果各年龄段宫颈HPV的阳性感染率均较高,17岁组感染率最低（20.0%）,50岁组最高（38.2%）。是否绝经、性伴侣数、避孕方式和饮酒与HPV感染显著相关（P〈0.05）。结论专一的性伴侣、采用避孕套避孕和不饮酒能降低HPV感染几率。

Epidemiological Survev on HPV Infection of Uterine Cervix Among the Women in the South of Hunan Province

Objective To study the infection of HPV in the south area of Hunan province and investigate the relationship between HPV infection of female cervix and the potential factors of female physiological phases,sexual behavior and life customs,etc. Methods Samples of cervical and vaginal excretion from 1,108 outpatient women were collected in The First People’s Hospital of Chen Zhou from Jan.2009 to Oct.2010 and twenty-one genotypes of HPV were detected in the samples.The ages,educational background,profession,registered permanent residence,menopause,the age of first intercourse,number of sexual partners,times of pregnancy,the age of first pregnancy,abortion,times of delivery,the ways of contraception,smoke and drinking were inquired.Chi square test were used for data analysis by SPSS 13.0. Results The proportions of HPV infection in different ages were all high,which the group for the age of 17 was lowest(20.0%),the group for the age of 50 was highest(38.2%).The correlation between infection of HPV and menopause,number of sexual partners,the ways of contraception and drinking was distinct(P<0.05). Conclusion No more than one sexual partner,using of condom and no drinking can prevent from infection of HPV.