| 短期吸入小剂量糖皮质激素对哮喘患儿骨转换指标影响的研究 |
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| 引用本文： | 王瑛,李美珠. 短期吸入小剂量糖皮质激素对哮喘患儿骨转换指标影响的研究[J]. 中国实用儿科杂志, 1999, 0(4) |
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| 作者姓名： | 王瑛 李美珠 |
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| 作者单位： | 北京医科大学第三临床医院儿科(王瑛),广州市儿童医院神经康复病区(李美珠) |
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| 摘 要： | 目的研究短期吸入小剂量糖皮质激素对哮喘儿童骨转换指标的影响。方法对８例无激素治疗史哮喘儿童持续吸入二丙酸倍氯米松（ＢＤＰ）２００～３００μｇ／ｄ,疗程１～２个月。疗程开始与结束时分别检测血清钙、磷、碱性磷酸酶、骨钙素及尿羟脯氨酸／肌酐比值。结果吸入ＢＤＰ１～２个月后患儿血清骨钙素水平下降了２０５６％,Ｐ＜００５,而血钙、磷、碱性磷酸酶水平和尿羟脯氨酸／肌酐比值无明显改变。结论短期内吸入ＢＤＰ２００～３００μｇ／ｄ有可能发生骨生成抑制。有必要对血清骨钙素水平进行长期动态观察
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| 关 键 词： | 吸入激素 哮喘儿童 骨转换 |
Effects of short-term treatment with inhaled glucocorticoids on markers of bone turnover in children with asthma |
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| Wang Ying,Li Meizhu. Effects of short-term treatment with inhaled glucocorticoids on markers of bone turnover in children with asthma[J]. Chinese Journal of Practical Pediatrics, 1999, 0(4) |
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| Authors: | Wang Ying Li Meizhu |
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| Affiliation: | Wang Ying,Li Meizhu Department of Pediatrics,The Third Clinical Hospital of Beijing Medical University,Beijing 100083 |
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| Abstract: | |
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| Keywords: | Inhaled glucocorticoids Childhood asthma Bone turnover |
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