| 慢性乙型重症肝炎及肝癌与血清可溶性Fas可溶性Fas配体 … |
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| 引用本文： | 宋卫青,吕维红.慢性乙型重症肝炎及肝癌与血清可溶性Fas可溶性Fas配体 …[J].中华检验医学杂志,2000,23(4):223-225. |
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| 作者姓名： | 宋卫青 吕维红 |
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| 作者单位： | 青岛市市立医院 |
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| 摘 要： | 目的 探讨血清可溶性Ｆａｓ／可溶性Ｆａｓ配体水平与慢性乙型重症肝炎以及乙肝病毒相关性肝细胞癌变之间的关系。方法 用酶联免疫吸附双抗体夹心法检测２１例无症状乙肝病毒携带者，２０例慢性乙型重症肝炎及２２例乙肝病毒相关性肝细胞癌患者血清ｓＦａｓ、ｓＦａｓＬ水平。结果 与无症状乙肝病毒携带者比较，慢性乙肝重症肝炎患者血清ｓＦａｓ、ｓＦａｓＬ水平均增高，其差异有显著意义；乙肝病毒相关性肝细胞癌患者ｓＦａｓ水
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| 关 键 词： | 可溶性Fas 可溶性Fas配体 慢性乙型肝炎 肝肿瘤 |
| 修稿时间： | 1999-12-08 |
Ralationship between serum soluble Fas/soluble Fas ligand and chronic serious hepatitis B/hepotocellular carcinoma |
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| SONG Weiqing,LU Weihong,HOU Wei,et al..Ralationship between serum soluble Fas/soluble Fas ligand and chronic serious hepatitis B/hepotocellular carcinoma[J].Chinese Journal of Laboratory Medicine,2000,23(4):223-225. |
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| Authors: | SONG Weiqing LU Weihong HOU Wei |
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| Institution: | SONG Weiqing,LU Weihong,HOU Wei,et al. Qingdao Municipal Hospital,Qingdao 266011,China |
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| Abstract: | Objective To study the relationship between soluble Fas/soluble Fas Ligand levels in serum and chronic serious hepatitis B/ hepotocellular carcinoma.Methods Soluble Fas (sFas) and soluble Fas Ligand (sFasL) levels in serum were measured in 21 patients with asymptomatic HBsAg carriers ,20 patients with chronic serious hepatitis B, and 22 patients with hepotocellular carcinoma by enzyme Linked immunosorbent assay (ELISA).Results Compared with asymptomatic HBsAg carriers, the sFas and sFasL levels in serum of patients with chronic serious hepatitis B were both significantly increased ( P <0.01) the sFas level was significantly increased, whereas the sFasL level being decreased.Conclusion There was significant relationship between sFas/sFasL levels and chronic serious hepatitis B/hepotocellular carcinoma. |
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| Keywords: | Soluble Fas Soluble Fas ligand Chronic serious hepatitis B |
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