抗痨凝胶介入治疗耐多药肺结核空洞的临床研究

目的探讨抗痨凝胶空洞介入治疗耐多药肺结核的临床疗效。方法利用介入放射学技术，以纤维支气管镜为介导，经气道-空洞引流支气管，将抗痨凝胶定期注入空洞，以放射学等指标观察疗效。结果治疗组比对照组空洞闭合率、痰菌阴转率均增高。未发现与抗痨凝胶有关的毒副作用。结论抗痨凝胶空洞介入是治疗耐多药肺结核的有效方法，未见明显毒副作用。

A study of treatment effects on antiphthisic gel in the interventional treatment of MDR-TB

Objective To discuss the clinical effectiveness of antiphthisic gel in the interventional treatment of MDR-TB. Methods Interventional radiologic technique was used, along with bronchofiberscope. Antiphthisic gel was injected through air tube-cavity draining bronchi into cavity regularly and the curative effect of using radiology index was observed. Results For the sputum negative rate and closure rate, the therapy group was higher than that in the control group. There had not been any observed adverse reaction in the process of interventional therapy. Conclusions Antiphthisic gel in the interventional treatment is safe and effective in the treatment of MDR -TB. There is no obvious side effect in the treatment.