糖尿病足患者骨密度及其相关危险因素研究

目的:探讨糖尿病足患者骨密度改变情况及相关危险因素。方法:测定糖尿病(DM)患者、糖尿病足(DF)患者和正常人腰椎(L2-4)、股骨颈、Ward区、大转子的骨密度(BMD),比较3组不同部位间骨密度有无差异,并用logistic回归方法分析糖尿病足的危险因素。结果:DM组与正常对照组的BMD比较差异无统计学意义(P>0.05),DF组的BMD低于正常对照组和DM组(P<0.05)。骨质疏松与DF的发生具有较强相关性。结论:应对糖尿病患者进行骨质疏松的监测及治疗,预防糖尿病足的发生。

Research on bone mineral density and related risk factors in patients with diabetic foot

Objective： To explore the changes of bone mineral density（BMD） and related risk factors in patients with diabetic foot. Methods： The bone mineral densities of lumbar （L2.4） , femoral neck, Ward＇ s area and greater trochanter were measured and compared between diabetes mellitus （DM） group, diabetic foot （DF） group and healthy group. The related risk factors of diabetic foot were analyzed by logistic regression method. Results： There was no significant difference of BMD between DM group and healthy group （P 〉 0.05）. The BMD level in DF group was lower than healthy group and DM group （P 〈 0.05）. Osteoporosis was closely correlated with DF. Conclusion： For patients with diabetes, BMD should be regularly monitored in order to prevent the happening of diabetic foot.