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Symptom dimensions in recent-onset schizophrenia and mania: a principal components analysis of the 24-item Brief Psychiatric Rating Scale
Authors:Ventura J  Nuechterlein K H  Subotnik K L  Gutkind D  Gilbert E A
Affiliation:

a UCLA Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA 90095-6968, USA

b UCLA Department of Psychology, Los Angeles, CA 90095-6968, USA

Abstract:Previous four- and five-factor solutions of the 18-item Brief Psychiatric Rating Scale (BPRS) suggested the possibility of an affective dimension in psychosis. A principal components analysis was used to analyze psychiatric symptom data rated on an expanded 24-item version of the BPRS. BPRS data were collected during a period of acute psychotic and affective illness with 114 young adult, recent-onset schizophrenia and schizoaffective patients and 27 bipolar manic patients. Principal components analyses of the 18-item and 24-item BPRS indicated a four-factor solution was the most interpretable. Principal components analysis of the 24-item BPRS produced a clear mania factor characterized by high loadings from items added to the 18-item BPRS, which included elevated mood, motor hyperactivity, and distractibility. This factor solution suggests that the 24-item BPRS allows for an expanded assessment of affective symptoms relating to a manic dimension. Potentially important symptoms that were added to the traditional 18-item version, namely suicidality, bizarre behavior, and self-neglect, also make clear contributions to other factors.
Keywords:Factor analysis   Schizoaffective disorder   Bipolar disorder   Brief Psychiatric Rating Scale   Schizophrenia
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