| 实验性糖尿病大鼠血清肿瘤坏死因子的变化 |
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| 引用本文： | 张书捷,包海花,高雪玲,陶惠然. 实验性糖尿病大鼠血清肿瘤坏死因子的变化[J]. 牡丹江医学院学报, 2000, 21(1): 5-6 |
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| 作者姓名： | 张书捷 包海花 高雪玲 陶惠然 |
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| 作者单位： | 牡丹江医学院,157011 |
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| 摘 要： | 目的：观察实验性糖尿病大鼠血清肿瘤坏死因子的变化。方法：用链脲佐菌素复制大鼠糖尿病模型，动态观察正常组大鼠及糖尿病组大鼠（３ｄ、７ｄ、２８ｄ）血糖和血清肿瘤坏死因子的水平。结果：糖尿病大鼠血糖呈持续性升高，明显高于正常大鼠（Ｐ〈０．００１）血甭肿瘤坏死因子，２８ｄ时明显高于正常级（Ｐ〈０．０１）。结论：肿瘤坏死因子是糖尿病大鼠胰岛损伤过程中的重要因素之一。
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| 关 键 词： | 实验性 糖尿病 血糖 血清肿瘤坏死因子 |
Change of tumor necrosis factor (TNF)in serum on experimental diabetic rats |
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| Zhang shu jie et al Mudanjiang Medical college. Change of tumor necrosis factor (TNF)in serum on experimental diabetic rats[J]. Journal of Mudanjiang Medical College, 2000, 21(1): 5-6 |
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| Authors: | Zhang shu jie et al Mudanjiang Medical college |
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| Affiliation: | Zhang shu jie et al Mudanjiang Medical college 157011 |
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| Abstract: | o b j e c t i ve :To observe the change of serurm glucse and serum TNF in experi- mental Diabetic rats.M e t h od Using streptozotocin(STZ)induced Diabetic experimental models in rats.We ynami-cally observed the levels of serum glucose and TNF (3.7.28 days ) R e s u l t :The results showed that the level of serum glucose was increassed significantly Comparign with the control group(P<0.01).The level of serum TNF was increased singnificantly at 28day than control group (P<0.01).C o n c l u s i o n s:TNF was one of important factors in pancreatic islet injuried of diabetic rats. |
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| Keywords: | exeperimental dibetic serum glucose serum TNF |
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