低温冷冻同种异体胎软骨移植的应用

目的 探讨同种异体胎软骨在整形外科应用的可行性。方法 在无菌条件下切取死胎儿的四肢及肋软骨，经低温保护剂进行超低温冷冻－８０℃，保存于－１９６℃的液氮中。经复温处理后应用于临床３８例。其中鞍鼻畸形２４例，外耳缺损４例，唇裂继发畸形６例，颏成形４例。结果 经３年６个月随访。除２例外耳再造术后出现变形外，其余病例均无吸收、变形、免疫排斥反应，外形较为满意。结论 同种异体胎儿软骨在整形外科有一定的应用价

Allotransplantation of cryopreserved fetal cartilage in plastic surgery]

OBJECTIVE: To study the applicability of homologous fetal cartilage in plastic surgery. METHODS: Limb and costal cartilage were taken from the dead fetus. The fetal cartilage was then frozen at -80 degrees C and preserved in -196 degrees C liquid nitrogen with a cryoprotective agent. A total of 38 patients received fetal cartilage transplantation. Of them there were 24 saddle nose, 4 auricle defects, 6 secondary deformities of cheiloschisis, 4 mandible deformities. RESULTS: Through follow-up of three and a half years, it was found that none of the transplanted cartilage was absorbed, deformed or rejected due to immunological reaction. The contours were satisfactory except 2 cases with auricle reconstruction. CONCLUSION: The clinical application of homologous fetal cartilages is of value in plastic surgery.