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电针呼循穴区对心律失常模型大鼠的影响
引用本文:王珊珊,李开春,李青润,石玉迎,张明章,潘锋,张露芬. 电针呼循穴区对心律失常模型大鼠的影响[J]. 中国中医急症, 2012, 21(6): 908-910
作者姓名:王珊珊  李开春  李青润  石玉迎  张明章  潘锋  张露芬
作者单位:1. 三峡大学第一临床医学院宜昌市中心人民医院,湖北宜昌,443003
2. 云南省昆明夕阳红老年病医院,云南昆明,650031
3. 宁夏回族自治区中医研究院,宁夏银川,750021
4. 中日友好医院,北京,100029
5. 承德医学院附属医院,河北承德,067000
6. 云南省曲靖市中医院,云南曲靖,655000
7. 北京中医药大学,北京,100029
基金项目:国家大学生创新性实验计划项目
摘    要:目的观察电针"呼循穴区"对心律失常大鼠的心电图及血浆环磷酸腺苷(cAMP)、环磷酸鸟苷(cGMP)水平的影响。方法采用BaCl2诱发大鼠心律失常模型,电针大鼠呼循穴区,观察实验前后各时刻大鼠心电图变化,检测干预后大鼠血浆cAMP、cGMP含量,并与电针额旁1线,舌下静脉注射0.5%利多卡因进行对比。结果电针呼循穴区能减慢心律失常大鼠心率、缩短复律时间,降低血浆cAMP、cAMP/cGMP水平,电针呼偱穴区与额旁1线效果相当,0.5%利多卡因效果最强。结论电针呼循穴区对心律失常大鼠有明显的改善作用,其作用机制可能与经络、自主神经系统,血浆cAMP、cGMP水平有关。

关 键 词:呼循穴区  电针  心律失常

Experimental Research on Electro-acupuncture Huxun Point Area in Arrhythmia Rats
Affiliation:WANG Shan-shan1,LI Kai-chun2,LI Qing-run3,et al.1 The First College of Clinical Medical Science,China Three Gorges University,Yichang Central People’s Hospital,Hubei,Yichang,443003;2 Xiyanghong Senile Disease Hospital of Kunming City,Yunan Province,Yunan,Kunming,650031;3 Ningxia Chinese Medicine Research Center,Ningxia,Yinchuan,750021
Abstract:Objective: To observe the effects of electro-acupuncture(EA) in arrhythmia rats via ECG,plasma cAMP and cGMP levels.Methods: Experimental arrhythmia model was induced by BaCl2 in rats with EA on Huxun point area or lateral line 1 of fore-head or intravenous inject lidocaine.Some indices were observed such as the ECG,the cAMP and the cGMP.Results: After the EA on Huxun point area,the heart rate and the cardioversion time were decreased.Levels including cAMP and cAMP / cGMP were reduced.The effect of EA on Huxun point area was similar to EA on lateral line 1 offore-head.Moreover,the intravenous inject lidocaine had the strongest effect.Conclusion: EA on Huxun point area has an obvious curative effect in arrhythmia rats.Its mechanism maybe related to the meridians,the autonomic nervous system,the cAMP and the cGMP.
Keywords:Huxun point area  Electro acupuncture  Arrhythmia
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