电针呼循穴区对心律失常模型大鼠的影响 |
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引用本文: | 王珊珊,李开春,李青润,石玉迎,张明章,潘锋,张露芬. 电针呼循穴区对心律失常模型大鼠的影响[J]. 中国中医急症, 2012, 21(6): 908-910 |
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作者姓名: | 王珊珊 李开春 李青润 石玉迎 张明章 潘锋 张露芬 |
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作者单位: | 1. 三峡大学第一临床医学院宜昌市中心人民医院,湖北宜昌,443003 2. 云南省昆明夕阳红老年病医院,云南昆明,650031 3. 宁夏回族自治区中医研究院,宁夏银川,750021 4. 中日友好医院,北京,100029 5. 承德医学院附属医院,河北承德,067000 6. 云南省曲靖市中医院,云南曲靖,655000 7. 北京中医药大学,北京,100029 |
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基金项目: | 国家大学生创新性实验计划项目 |
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摘 要: | 目的观察电针"呼循穴区"对心律失常大鼠的心电图及血浆环磷酸腺苷(cAMP)、环磷酸鸟苷(cGMP)水平的影响。方法采用BaCl2诱发大鼠心律失常模型,电针大鼠呼循穴区,观察实验前后各时刻大鼠心电图变化,检测干预后大鼠血浆cAMP、cGMP含量,并与电针额旁1线,舌下静脉注射0.5%利多卡因进行对比。结果电针呼循穴区能减慢心律失常大鼠心率、缩短复律时间,降低血浆cAMP、cAMP/cGMP水平,电针呼偱穴区与额旁1线效果相当,0.5%利多卡因效果最强。结论电针呼循穴区对心律失常大鼠有明显的改善作用,其作用机制可能与经络、自主神经系统,血浆cAMP、cGMP水平有关。
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关 键 词: | 呼循穴区 电针 心律失常 |
Experimental Research on Electro-acupuncture Huxun Point Area in Arrhythmia Rats |
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Affiliation: | WANG Shan-shan1,LI Kai-chun2,LI Qing-run3,et al.1 The First College of Clinical Medical Science,China Three Gorges University,Yichang Central People’s Hospital,Hubei,Yichang,443003;2 Xiyanghong Senile Disease Hospital of Kunming City,Yunan Province,Yunan,Kunming,650031;3 Ningxia Chinese Medicine Research Center,Ningxia,Yinchuan,750021 |
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Abstract: | Objective: To observe the effects of electro-acupuncture(EA) in arrhythmia rats via ECG,plasma cAMP and cGMP levels.Methods: Experimental arrhythmia model was induced by BaCl2 in rats with EA on Huxun point area or lateral line 1 of fore-head or intravenous inject lidocaine.Some indices were observed such as the ECG,the cAMP and the cGMP.Results: After the EA on Huxun point area,the heart rate and the cardioversion time were decreased.Levels including cAMP and cAMP / cGMP were reduced.The effect of EA on Huxun point area was similar to EA on lateral line 1 offore-head.Moreover,the intravenous inject lidocaine had the strongest effect.Conclusion: EA on Huxun point area has an obvious curative effect in arrhythmia rats.Its mechanism maybe related to the meridians,the autonomic nervous system,the cAMP and the cGMP. |
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Keywords: | Huxun point area Electro acupuncture Arrhythmia |
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