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Enterotoxigenic and necrotizing Escherichia coli in human diarrhoea in Spain
Authors:J Blanco  E A González  P Espinosa  M Blanco  J I Garabal  M P Alonso
Institution:(1) Departamento de Microbiologia y Parasitologia - Facultad de Veterinaria, Universidad de Santiago, Lugo, Spain;(2) Servicio de Bacteriología - Centro Nacional de Microbiología, Virologia e Immunologia Sanitarias, Instituto Nacional de la Salud, Majadahonda, Madrid, Spain;(3) Unidad de Microbiologia, Hospital Xeral, Lugo, Spain
Abstract:Enterotoxigenic Escherichia coli (ETEC) strains of serotype 0153: K-:H45 CFA/I+ STa+ were associated with two outbreaks of neonatal diarrhoea that occurred in two different hospitals of Madrid, in one of which several children died. Two other outbreaks were associated with ETEC strains of serotypes 0159: K-: H21 (LT+) and 0159: K-: H4 (LT+ STa+) without CFA/I and CFA/II colonization factors. Necrotizing E. coli (NTEC) strains of serotype 06: K13, producing the cytotoxic necrotizing factor CNFI and agr-haemolysin, were also associated with two outbreaks of neonatal diarrhoea that occured in a hospital in Madrid and in a hospital in Talavera de la Reina. The results of the characterization of some ETEC and NTEC strains isolated from sporadic cases of diarrhoea are also discussed.Corresponding author.
Keywords:Enterotoxins  Necrotizing factors  E  coli
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