脑卒中急性期空腹血糖、糖化血红蛋白A1c及乳酸脱氢酸的测定

目的探讨急性脑卒中时空腹血糖(FBS)、糖化血红蛋白A1 c(HbA1 c)和乳酸脱氢酶(LDH)联合测定的临床意义。方法50例急性脑卒中患者进行欧洲脑卒中(ESS)评分,测定FBS、HbA1 c、LDH及中性粒细胞(NEUT)比例,按疾病类型及FBS与HbA1 c联合两种方法分组,比较各组间指标差异。结果脑出血组的ESS评分低于脑梗死组,NEUT高比例的发生率及LDH水平高于脑梗死组(P<0.05),非糖尿病性高血糖组ESS评分低于正常血糖组(P<0.01)和糖尿病性高血糖组(P<0.05),NEUT高比例的发生率及LDH水平高于正常血糖组(P<0.01)和糖尿病性高血糖组(P<0.05)。结论高FBS伴HbA1 c正常的急性脑卒中患者的LDH水平高,病情重。

Values of blood glucose and glycosylated hemoglobin combined with lactate dehydrogenase in acute stroke patients

Objective To investigate the clinical significance of blood glucose and HbA1c combined with lactate dehydrogenase in acute stroke patients.Methods The study involved 50 patients hospitalized with acute stroke who were divided into different groups by types of stroke and FBS with HbAlc.ESS scores,blood pressure,fast blood glucose,HbAlc,serum lipids,LDH and percentage of neutrophil were also measured.Results Compared with ischemic strokes,ESS scores were significantly lower in hemorrhagic strokes,but the level of LDH and the incidence of the high percentage of neutrophil were higher(P<(0.05)).ESS score in cases of hyperglycaemia without DM was significantly lower than that in normal FBS(P<(0.01)) and hyperglycaemia with DM(P<(0.05)).The level of LDH and the incidence of the high percentage of neutrophil in cases of hyperglycaemia without DM were higher than those in normal FBS(P<(0.01)) and hyperglycaemia with DM(P<(0.05)).Conclusions The results suggest that acute stroke patients who have hyperglycaemia with normal HbAlc have higher levels of LDH and more critical conditions.