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314例药品不良反应报告分析
引用本文:郝红兵,马辛.314例药品不良反应报告分析[J].中国医院用药评价与分析,2011(3):272-274.
作者姓名:郝红兵  马辛
作者单位:首都医科大学附属北京安定医院药剂科;
摘    要:目的:探讨精神疾病专科医院药品不良反应(ADR)的特点及规律,促进临床合理用药。方法:采用回顾性分析方法,对我院上报的314例ADR报表,按患者性别、年龄、疾病诊断、给药途径、ADR报表分类及其药品使用情况、ADR涉及器官或系统、引起ADR最多的前10种药物及主要临床表现进行分析。结果:314例ADR患者中,女性多于男性;21~40岁发生率较高;精神分裂症占多数;口服药发生的ADR更常见;一般的ADR占多数;ADR涉及最多的为神经系统;喹硫平的ADR发生率最高。结论:精神疾病专科医院发生的ADR多涉及神经系统,给患者造成的危害较大,临床应给予高度关注与及时治疗。

关 键 词:药品不良反应  报告  分析

Adverse Drug Reactions:Analysis of 314 Cases
HAO Hong-bing,MA Xin.Adverse Drug Reactions:Analysis of 314 Cases[J].Evaluation and Analysis of Drug-Use in Hospital of China,2011(3):272-274.
Authors:HAO Hong-bing  MA Xin
Institution:HAO Hong-bing,MA Xin(Dept. of Pharmacy,Beijing Anding Hospital Affiliated to Capital Medical University,Beijing 100088,China)
Abstract:OBJECTIVE:To probe into the characteristics and regularity of the adverse drug reactions(ADRs) occurred in psychiatric hospital to promote rational clinical drug use.METHODS:By a retrospective analysis,a total of 314 ADR cases reported by our hospital were analyzed with regard to patients' age and sex,diagnosis,route of administration,category of ADR reports,drug use,ADR-involved organs or systems,the top 10 drugs in terms of ADR incidence and the major clinical manifestations.RESULTS:Of the 314 ADR cases,f...
Keywords:Adverse drug reaction(ADR)  Reports  Analysis  
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