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复方苦参注射液联合顺铂治疗恶性胸腔积液的疗效观察
引用本文:冉凤鸣,臧爱华.复方苦参注射液联合顺铂治疗恶性胸腔积液的疗效观察[J].中国医院用药评价与分析,2011(8):739-740.
作者姓名:冉凤鸣  臧爱华
作者单位:湖北省肿瘤医院肿瘤内科;
摘    要:目的:探讨复方苦参注射液+顺铂(PDD)胸腔内注入治疗恶性胸腔积液的疗效与不良反应。方法:经病理或胸水细胞学确诊为恶性胸腔积液的患者共60例,采用随机抽样方法分为复方苦参注射液+PDD组(观察组)与单用PDD组(对照组)各30例。观察组胸腔内注入复方苦参注射液25 mL+0.9%氯化钠注射液40 mL+PDD 40 mg+地塞米松5 mg;对照组胸腔内注入0.9%氯化钠注射液40 mL+PDD 60 mg+地塞米松5 mg,5~7 d后重复注射,最多重复4次,观察疗效、生活质量、不良反应。结果:观察组总有效率为86.7%,对照组为60%(P<0.05);且观察组不良反应较对照组轻。结论:胸腔内注入复方苦参注射液+PDD治疗恶性胸腔积液疗效优于单用PDD,且可提高患者生活质量。

关 键 词:复方苦参注射液  顺铂  恶性胸腔积液

Efficacy of Compound Kushen Injection Combined with Cisplatin for Malignant Pleural Effusion
RAN Feng-ming,ZANG Ai-hua.Efficacy of Compound Kushen Injection Combined with Cisplatin for Malignant Pleural Effusion[J].Evaluation and Analysis of Drug-Use in Hospital of China,2011(8):739-740.
Authors:RAN Feng-ming  ZANG Ai-hua
Institution:RAN Feng-ming,ZANG Ai-hua(Dept. of Oncology,Hubei Provincial Tumor Hospital,Wuhan 430079,China)
Abstract:OBJECTIVE:To evaluate the efficacy and adverse reactions of Compound Kushen injection combined with Cisplatin injected intrapleurally for patients with malignant pleural effusion.METHODS:A total of 60 patients with malignant pleural effusion as confirmed by histology or cytology of pleural fluid were randomly assigned to either control group or trial group.In the trial group,the patients were treated with Compound Kushen injection(25 mL) plus 0.9% normal saline(40 mL),Cisplatin(40 mg) and dexamethasone(5 mg...
Keywords:Compound Kushen injection  Cisplation(PDD)  Malignant pleural effusion  
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