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经皮冠状动脉支架介入治疗患者行非心脏手术抗血小板治疗的困惑与思考
引用本文:龚俊松,袁贵秀,陈晓东,彭勇刚.经皮冠状动脉支架介入治疗患者行非心脏手术抗血小板治疗的困惑与思考[J].国际麻醉学与复苏杂志,2021,42(1):68-74.
作者姓名:龚俊松  袁贵秀  陈晓东  彭勇刚
作者单位:中国医学科学院,北京协和医学院,国家心血管病中心,阜外医院麻醉科 100037;中南大学湘雅二医院麻醉科,长沙 410011;南京医科大学第一附属医院麻醉科 210029;佛罗里达大学附属Shands医院麻醉科,盖恩斯维尔 32608,美国
摘    要:冠状动脉粥样硬化性心脏病患者日益增多,其中有相当比例的患者接受了经皮冠状动脉介入治疗及术后双联抗血小板治疗。这些患者如果短期内需要接受非心脏手术将面临失血增加的危害,但是如果停止抗血小板治疗,围手术期支架内血栓形成的风险和心肌梗死的发生率将增加。文章针对上述问题就冠状动脉支架植入患者术后抗凝治疗的主要药物、有效性及安全...

关 键 词:冠状动脉粥样硬化性心脏病  经皮冠状动脉介入治疗  抗血小板治疗

Confusion and thoughts on antiplatelet therapy in non-cardiac surgery for patients undergoing percutaneous coronary intervention
Gong Junsong,Yuan Guixiu,Chen Xiaodong,Peng Yonggang.Confusion and thoughts on antiplatelet therapy in non-cardiac surgery for patients undergoing percutaneous coronary intervention[J].international journal of anesthesiology and resuscitation,2021,42(1):68-74.
Authors:Gong Junsong  Yuan Guixiu  Chen Xiaodong  Peng Yonggang
Institution:(Department of Anesthesiology,Fuwai Hospital,National Center for Cardiovascular Diseases,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing 100037,China;Department of Anesthesiology,the Second Xiangya Hospital of Central South University,Changsha 410011,China;Department of Anesthesiology,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China;Department of Anesthesiology,Shands Hospital,University of Florida,Gainesville 32608,USA)
Abstract:The number of patients with coronary atherosclerotic heart disease is increasing,and a great part of the patients undergo percutaneous coronary intervention followed by postoperative dual antiplatelet therapy.These patients will face an increasing risk of blood loss if a non-cardiac surgery is needed within a short period of time.However,once antiplatelet therapy stops,they will also face an increasing risk of perioperative stent thrombosis and myocardial infarction.This article focuses on a series of issues related to antiplatelet therapy,including common medicine,effectiveness and safety,antiplatelet therapy duration,complications,withdrawal protocol,and bridging management,in order to improve perioperative safety.
Keywords:Coronary atherosclerotic heart disease  Percutaneous coronary interventional therapy  Antiplatelet therapy
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