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Systematic review on the evidences of an association between tinnitus and depression
Authors:Luciana Geocze  Samantha Mucci  Denise Caluta Abranches  Mario Alfredo de Marco  Norma de Oliveira Penido
Affiliation:MSc; PhD student. Psychologist - Medical School of the Federal University of São Paulo -UNIFESP-EPM;PhD. Post-Doctoral program. DDS - UNIFESP-EPM;PhD. Associate Professor of Psychiatry - UNIFESP-EPM;Post-Doctoral Degree - Adjunct Professor of Otorhinolaryngology - UNIFESP-EPM. Department of Otorhinolaryngology and Head and Neck Surgery, Federal University of São Paulo - UNIFESP-EPM
Abstract:Tinnitus has been associated with several psychiatric disorders, however there are still several questions regarding such association.ObjectiveTo assess the scientific evidence on the associations between symptoms of depression, depression, and tinnitus.MethodA systematic review was performed using PubMed, Lilacs, and SciELO scientific databases. This review included studies published in Portuguese, Spanish, or English correlating tinnitus with depression; letters to the editor and case reports were excluded.ResultsA total of 64 studies were identified, of which only 20 met the inclusion criteria and only 2 were case-control clinical trials. The majority of the studies (n = 18) found that depression is associated with tinnitus, either as a predisposition - resulting in poor adaptation to tinnitus or as a consequence of severe disease.ConclusionAn overall assessment of all of the selected studies suggests at least 3 possible associations between depression and tinnitus: depression affecting tinnitus, tinnitus predisposing individuals to depression, and tinnitus appearing as a comorbidity in patients with depression. There is a high prevalence of depressive symptoms in individuals with tinnitus, but the mechanisms by which depression and tinnitus mutually interact, are not fully understood.
Keywords:depression  review  symptoms  tinnitus
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