| Abstract: | Obesity poses unique challenges for the ICU team. Important changes in cardiovascular, pulmonary and immunologic physiology predispose such patients to respiratory failure, thromboembolic disease, abdominal compartment syndrome, and aspiration. Special attention is required when performing routine ICU procedures, such as intubation and insertion of central venous catheters, and limitations in testing capabilities may lead the astute ICU clinician to rely solely on clinical suspicion when making therapeutic decisions. Daily management can be further hampered by uncertainties regarding drug metabolism and pharmacokinetics, nutritional needs, and challenges in bedside nursing care. |
