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Value of immunohistochemistry in the diagnosis of malignant cervical lymph nodes
Authors:Décio de Natale Caly  Abrão Rapoport  Otávio Alberto Curioni  Rogério Aparecido Dedivitis  Claudio Roberto Cernea  Lenine Garcia Brandão
Institution:1. PhD in Pathology - AC Camargo Hospital. Pathologist - Heliopolis Hospital - São Paulo.;2. Senior Associate Professor - Department of Surgery, Medical School - University of São Paulo. Technical Director of the Department of Health - Heliopolis Hospital, São Paulo and São José Hospital Surgeon at the RBBP, São Paulo.;3. Senior Associate Professor - Department of Surgery - Lusiada Foundation - Santos. Head of the Department of Head and Neck Surgery and Otorhinolaryngology - Heliópolis Hospital - São Paulo and Surgeon - São José Hospital - RBBP, São Paulo.;4. MD. Full Professor. Larynx Group Supervisor - Department of Head and Neck Surgery, University Hospital - Medical School - University of São Paulo.;5. Associate Professor - Department of Head and Neck Surgery, Medical School - University of São Paulo.;6. Full Professor - Department of Head and Neck Surgery, Medical School - University of São Paulo. Department of Head and Neck Surgery, Medical School - University of São Paulo.
Abstract:The cervical lymph nodes are relevant due to the diversity of clinical entities. The use of immunohistochemistry is a real method to elucidate the diagnosis of adenopathy, both primary and metastatic neoplasms.ObjectiveTo assess the value of immunohistochemistry in the diagnosis of cervical lymph nodes malignancies.MethodRetrospective study of the database histopathological specimens from 2009 to 2011.ResultsOut of 32 biopsies of cervical lymph nodes, in 16 (50%) the immunohistochemistry was employed, being 68.75% (11) in hematological neoplasms and 31.25% (5) in carcinomas. It was used in all cases of lymphoma.ConclusionThe immunohistochemistry was used in 50% of the biopsies of lymph nodes under suspicion of malignancy, being 31.25% in epithelial lesions and 68.75% in lymphoproliferative lesions.
Keywords:carcinoma  squamous cell  immunohistochemistry  lymphatic diseases  lymphoma
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