| 达格列净片致正常血糖酮症2例分析 |
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| 引用本文： | 蔡俊,卫菁,纪立伟. 达格列净片致正常血糖酮症2例分析[J]. 中国药物警戒, 2021, 0(3): 271-273 |
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| 作者姓名： | 蔡俊 卫菁 纪立伟 |
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| 作者单位： | 南京大学医学院附属鼓楼医院药学部;南京中医药大学附属江苏省中医院药学部;北京医院药学部 |
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| 基金项目： | 江苏省药学会-天晴(连云港)医院药学科研项目(Q2019024);南京药学会-常州四药医院药学科研基金(2019YX016)。 |
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| 摘 要： | 目的 提高医务人员对达格列净片导致正常血糖酮症的警惕,为安全使用达格列净片提供参考.方法 分析2例由达格列净片导致正常血糖酮症患者的诊疗经过,结合国内外文献分析,探讨达格列净片导致正常血糖酮症的发生情况以及危险因素.结果 2例有糖尿病酮症病史的患者分别在使用达格列净片52 d和18 d后出现正常血糖酮症,立即停用达格列...
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| 关 键 词： | 达格列净片 正常血糖酮症 药品不良反应 |
Two Cases of Euglycemic Diabetic Ketosis Induced by Dapagliflozin Tablets |
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| CAI Jun,WEI Jing,JI Liwei. Two Cases of Euglycemic Diabetic Ketosis Induced by Dapagliflozin Tablets[J]. Chinese JOurnal of Pharmacovigilance, 2021, 0(3): 271-273 |
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| Authors: | CAI Jun WEI Jing JI Liwei |
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| Affiliation: | (Nanjing Drum Tower Hospital Affiliated to Medical College of Nanjing University,Nanjing Jiangsu 210008,China;Jiangsu Province Hospital of TCM Affiliated to Nanjing University of Chinese Medicine,Nanjing Jiangsu 210029,China;China Beijing Hospital,National Center of Gerontology,Beijing 100730,China) |
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| Abstract: | Objective To remind medical staff to be more vigilant about Dapagliflozin tablets-induced euglycemic diabetic ketosis,and provide reference for safe use of Dapagliflozin tablets.Methods The process of diagnosis and treatment of 2 patients with euglycemic diabetic ketosis caused by Dapagliflozin tablets was analyzed,and the incidence and related risk factors were analyzed based on domestic and foreign literature.Results Two patients with a history of diabetic ketosis developed euglycemic diabetic ketosis 52 and 18 days after taking Dapagliflozin tablets,respectively.Dapagliflozin tablets were discontinued immediately and insulin therapy was given.The ketone bodies turned negative.Conclusion Clinicians should be alert to the risk of euglycemic diabetic ketosis induced by Dapagliflozin tablets,especially in patients with a history of diabetic ketosis. |
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| Keywords: | Dapagliflozin tablets euglycemic diabetic ketosis adverse drug reactions |
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