A single-nucleotide polymorphism in the human bone morphogenetic protein-4 (BMP 4) gene |
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Authors: | Massimo Mangino Isabella Torrente Alessandro De Luca Otto Sanchez Bruno Dallapiccola Giuseppe Novelli |
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Institution: | (1) Cattedra di Genetica Umana e Medica, Dipartimento di Biopatologia e Diagnostica per Immagini, Università di Roma "Tor Vergata" e CSS Istituto Mendel, Roma, Via di Tor Vergata 135-00133 Roma, Italy Tel. +39-06-7259-6080; Fax +39-06-2042-7313 e-mail: novelli@med.uniroma2.it, IT;(2) Unidad de Genetica, Escuela de Medicina, Universidad de Oriente, Ciudad Bolivar, Venezuela, VE |
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Abstract: | A polymorphic site has been found in the human bone morphogenetic protein-4 (BMP4) gene. To our knowledge, it is the first defined polymorphism in this gene, being present with similar frequencies in Caucasian,
Hispanic, and African populations.
Received: July 21, 1998 / Accepted: August 25, 1998 |
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Keywords: | BMP4 Chromosome 14 Polymorphism Osteoporosis Arthritis |
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