Reaction of pulmonary tumor transplants to irradiation and platidiam in the subcapsular test |
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| Authors: | O I Skotnikova N S Sergeeva E V L'vova V I Chissov I I Pelevina |
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| Institution: | (1) A. Hertzen Moscow Research Oncological Institute, Ministry of Health of Russia, Moscow;(2) Institute of Chemical Physics, Russian Academy of Sciences, Moscow |
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| Abstract: | Effects of γ-irradiation in a dose of 6 Gy and platidiam in a total dose of 16 mg/kg on the growth rate of transplants of
20 human pulmonary carcinomas under the renal capsules of immunodepressed mice were studied. Ten out of 11 tumors resistant
to radiation were found to be resistant to platidiam as well. On the other hand, only 10 out of 15 carcinomas resistant to
platidiam were resistant to radiation.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N
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11, pp. 505–507, November, 1994 |
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| Keywords: | irradiation chemical agents pulmonary carcinomas subcapsular test |
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