| 内皮祖细胞与糖尿病血管并发症的研究进展 |
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| 引用本文： | 陈树春. 内皮祖细胞与糖尿病血管并发症的研究进展[J]. 心血管病学进展, 2010, 31(5): 759-762. DOI: 10.3969/j.issn.1004-3934.2010.05.037 |
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| 作者姓名： | 陈树春 |
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| 作者单位： | 河北省人民医院内分泌一科,河北,石家庄,050051 |
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| 摘 要： | 糖尿病的血管并发症是糖尿病致残致死的主要原因,其病理基础为血管内皮功能失调,而内皮祖细胞是血管内皮修复的重要物质,且与糖尿病以及血管疾病密切相关,被认为是心血管疾病的预测因子。现就内皮祖细胞与糖尿病及其血管并发症之间的关系以及研究进展进行综述。
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| 关 键 词： | 内皮祖细胞 内皮功能紊乱 内皮修复 糖尿病 并发症 |
Relationship Between Endothelial Progenitor Cells and Vascular Complications of Diabetes |
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| CHEN Shu-chun. Relationship Between Endothelial Progenitor Cells and Vascular Complications of Diabetes[J]. Advances in Cardiovascular Diseases, 2010, 31(5): 759-762. DOI: 10.3969/j.issn.1004-3934.2010.05.037 |
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| Authors: | CHEN Shu-chun |
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| Affiliation: | CHEN Shu-chun,SONG Guang-yao(The First Department of Endocrinology,The People＇s Hospital of Hebei Province,Shijiazhuang 050051,China) |
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| Abstract: | Vascular complications are the main reason for disabilities related to diabetes.The malfunction of endothelial progenitor cell（EPC） functionality is the early stage of vascular complication.Recent evidence has indicated that EPC contribute to the reendothelialization of injured vessels,and is related to both diabetes and vascular disease.A decrease in the number of EPC is an independent predictor of cardiovascular diseases.This article reviews recent research related to the vascular complications caused by diabetes and EPC. |
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| Keywords: | endothelial progenitor cells dysfunction of endothelial function reendothelialization diabetes complication |
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