| 加味黄芪合剂对被动吸烟大鼠肺损伤的保护作用研究 |
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| 引用本文： | 赵诚,管茶香,陈鹭姗,刘惠君,廖梅,张晓洁,张英东,王楠. 加味黄芪合剂对被动吸烟大鼠肺损伤的保护作用研究[J]. 实用预防医学, 2007, 14(6): 1658-1660 |
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| 作者姓名： | 赵诚 管茶香 陈鹭姗 刘惠君 廖梅 张晓洁 张英东 王楠 |
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| 作者单位： | 1. 中南大学湘雅医学院精神卫生03级,湖南,长沙,410078
2. 中南大学湘雅医学院生理学系,湖南,长沙,410078 |
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| 基金项目： | 中南大学大学生创新教育重点项目(YA06062) |
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| 摘 要： | 目的观察加味黄芪合剂对连续被动吸烟的大鼠肺损伤的影响。方法烟熏法建立被动吸烟大鼠模型,观察肺组织形态学及测定肺组织中超氧化物歧化酶(SOD)活性的变化,反映加味黄芪制剂对大鼠肺损伤的干预效果。结果加味黄芪合剂明显减轻被动吸烟大鼠的肺组织损伤,增加SOD活性。结论加味黄芪合剂对被动吸烟大鼠所致肺损伤具有一定的保护作用。
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| 关 键 词： | 被动吸烟 加味黄芪合剂 肺损伤 |
| 文章编号： | 1006-3110（2007）06-1658-03 |
| 收稿时间： | 2007-08-16 |
| 修稿时间： | 2007-08-16 |
Protective Effects of Astragalus Mixture on Lung Injury Induced by Passive Smoking in Rats |
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| ZHAO Cheng, GUAN Cha - xiang , CHEN Lu - shan ,et al.. Protective Effects of Astragalus Mixture on Lung Injury Induced by Passive Smoking in Rats[J]. Practical Preventive Medicine, 2007, 14(6): 1658-1660 |
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| Authors: | ZHAO Cheng GUAN Cha - xiang CHEN Lu - shan et al. |
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| Affiliation: | Grade 2003, Mental Health Department, Xiangya Medical School, Central South University, Changsha 410078, Hunan |
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| Abstract: | Objective To observe the influences of astragalus mixture on the lung injury caused by continuous passive smoking in rat models.Methods The passive smoking rat models were established to study the lung histopathology.The activity alterations of superoxide dismutase(SOD)in lung tissue were monitored and the effect of astragalus mixture intervention was observed.Results Astragalus mixture significantly reduced the lung injury in rat models of passive smoking and increased the activity of SOD.Conclusion Astragalus mixture has protective effects on the lung injury caused by passive smoking in rats. |
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| Keywords: | Passive smoking Astragalus mixture Lung injury |
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