褪黑素对慢性间歇性缺氧心肌的保护作用

褪黑素（melatonin，MLT）是由松果体分泌的一种重要的吲哚胺类激素，化学名称N-乙酰基-5-甲氧基色胺（N—acetyl-5-methoxytrypatmine）。MLT具有多种生理功能，除具有调节生物的昼夜节律、提高免疫力、改善睡眠、抗炎、抗氧化、抗肿瘤、抗衰老外，还影响心血管系统，有抗高血压、调节血脂代谢、抗心肌细胞损伤及对血管内皮保护的作用。本文就MLT生物学作用及对慢性间歇性缺氧性心肌保护作用进行简要综述。

Protective Effect of Melatonin on Chronic Intermittent Hypoxia Cardiac Muscular Tissue

Melatonin （melatonin, MLT）, is one of the most important indole amine hormone secreted by the pineal gland, whose chemical name is N-acetyl-5-methoxytrypatmine. MLT has many such physiological functions as adjusting biological circadian rhythms, enhancing immunity, improving sleep, anti-inflammation, anti-oxidation, antitumor and anti-aging. Besides, it can also affect the cardiovascular system, beating the functions of anti-hypertension, the regulation of lipid metabolism, resisting myocardial cell damage and the protection of vascular endothelial. This article will make a summary of MLT biological functions and protective effect of melatonin on chronic intermittent hypoxia cardiac muscular tissues.