Peripheral neuropathy, cerebral atrophy, and intellectual impairment in chronic alcoholics |
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| Authors: | B. Meldgaard,K. Andersen,P. Ahlgren,U. T. Danielsen,H. Sø rensen |
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| Affiliation: | Department of Neurology, University of Copenhagen, Glostrup, Denmark;Clinical Neurophysiology, Gentofte Hospital, Faculty of Medicine, University of Copenhagen, Hellerup, University of Copenhagen, Glostrup, Denmark;Department of Neuroradiology, Glostrup Hospital, Faculty of Medicine, University of Copenhagen, Glostrup, Denmark |
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| Abstract: | Peripheral neuropathy, cerebral atrophy, and intellectual impairment was investigated in 46 males with alcoholic nervous system damage. An overall correlation was found between peripheral neuropathy and cerebral atrophy and between several of the individual neurophysiological and neuroradiological variables examined. There was also a correlation between cerebral atrophy and intellectual impairment. The findings support the view that alcohol in itself is toxic to central and peripheral nervous tissues, although a dose-response dependence could not be established. |
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| Keywords: | Alcoholism cerebral atrophy intellectual impairment peripheral neuropathy |
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