系线的食管胶囊内镜对食管疾病的诊断价值

目的探讨改良的（系线）食管胶囊内镜在食管疾病诊断中的临床价值。方法对有食管相关症状的80例患者，先后进行系线的食管胶囊内镜检查和胃镜检查，对比2种检查方法的食管检查耗时、食管病变检出及不良反应发生情况。结果80例均顺利完成2种检查；食管检查平均耗时系线的食管胶囊内镜为（226．18±110．30）s，胃镜检查为（21．28±8．01）s，差异有统计学意义（t=-16．665，P=0．000）。2种检查方法共检出119处食管黏膜病变，两者诊断符合率为82．4％（98／119），其中10处食管癌病灶（经病理组织学检查证实）2种方法均全部检出，5处局灶鳞状上皮高级别上皮内瘤变和3处食管早期鳞癌病灶（8处均经组织学检查确诊）2种方法均提示食管黏膜粗糙。系线的食管胶囊内镜检查并发症总的发生率明显低于胃镜检查（1．3％比8．8％，x2=4．238，P=0．040），且吞咽胶囊困难发生率（P=0．022）、咽喉部不适发生率（P=0．007）及呕吐发生率（P=0．000）均明显低于胃镜检查。结论对于食管疾病诊断，系线的食管胶囊内镜检查操作简单、安全，患者易耐受，且诊断较为准确，可作为补充的检查方法。

Diagnostic value of stringed esophageal capsule endoscopy for the esophageal diseases

Objective To investigate the diagnostic value of the modified esophageal capsule endos- copy （stringed esophageal capsule endoscopy, SCE） for esophageal diseases. Methods A total of 80 pa- tients with esophageal related symptoms underwent SCE followed by esophagogastroduodenoscopy （EGD）. The examination time, detection rate of esophageal lesions, complications and adverse effects were compared. Results All patients completed the study. The mean examination time of SCE and EGD was 226. 18 ＋ 110. 30 seconds and 21.28 ＋8.01 seconds respectively （t = - 16. 665, P =0. 000）. A total of 119 lesions were detected by SCE and EGD, and the diagnostic accordance rate of SCE and EGD was 82.4% （98/119）. Ten lesions of advanced squamous carcinoma, 5 lesions of high grade intraepithelial neoplasia and 3 lesions of early squamous carcinoma were detected by both examinations, all of which were confirmed by histopatho- logic examination. The overall rate of complication in SCE （ 1.3%, 1/80） was significantly lower than that of EGD （8.8%, 7/80, X2 = 4. 238, P = 0. 040） and the rates of swallow difficulty （ P = 0. 022）, throat dis- comfort （ P = 0. 007） and vomiting （ P = 0. 000） of SCE were significantly lower than those of EGD. Con- clusion SCE is a feasible, easy-to-operate, safe, well tolerated and accurate method for detection of esopha- geal diseases, and could be a non-invasive alternative for conventional EGD.