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DPP-4抑制剂用于治疗2型糖尿病合并非酒精性脂肪肝的新进展
引用本文:王芬芬,张永莉.DPP-4抑制剂用于治疗2型糖尿病合并非酒精性脂肪肝的新进展[J].海南医学,2014(22):3361-3363.
作者姓名:王芬芬  张永莉
作者单位:延安大学附属医院东关分院综合内科,陕西 延安,716000
摘    要:二肽基肽酶Ⅳ抑制剂(DPP-4抑制剂)是一种新的糖尿病治疗药物,其能安全有效降糖,又能改善胰岛素抵抗,为2型糖尿病(T2DM)合并非酒精性脂肪肝(NAFLD)的转归提供一种新的可能,是近年研究的热点。本文就其在T2DM合并NAFLD治疗中可能的疗效和临床证据进行综述。

关 键 词:DPP-4抑制剂  2型糖尿病  非酒精性脂肪肝

Progress in DPP-4 inhibitors for the treatment of type 2 diabetes mellitus with non-alcoholic fatty liver
WANG Fen-fen,ZHANG Yong-li.Progress in DPP-4 inhibitors for the treatment of type 2 diabetes mellitus with non-alcoholic fatty liver[J].Hainan Medical Journal,2014(22):3361-3363.
Authors:WANG Fen-fen  ZHANG Yong-li
Institution:.( Comprehensive Department, East Branch of Affiliated Hospital of Yan'an University, Yan' an 716000, Shaanxi, CHINA)
Abstract:Dipeptidyl peptidase Ⅳ inhibitors(DPP-4 inhibitor) was a new oral drug for the treatment of diabetes, which not only decresed blood glucose safely and effectively, but also improved the insulin resistance and provided a new possibility for the outcome of type 2 diabetes mellitus(T2DM) patients with non-alcoholic fatty liver disease(NAFLD). This article reviewed its efficacy and clinical evidence of T2 DM with NAFLD.
Keywords:DPP-4 inhibitors  Type 2 diabetes mellitus  non-alcoholic fatty liver disease
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