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鲢鱼寡肽对高血脂大鼠脂质代谢的调节与抗氧化作用研究
引用本文:董士远,孟艳丽,赵元晖,刘尊英,曾名湧. 鲢鱼寡肽对高血脂大鼠脂质代谢的调节与抗氧化作用研究[J]. 营养学报, 2011, 33(2): 121-124
作者姓名:董士远  孟艳丽  赵元晖  刘尊英  曾名湧
作者单位:中国海洋大学食品科学与工程学院,青岛,266003
摘    要:目的 研究了鲢鱼寡肽(SOP)对高血脂Wistar大鼠的杭氧化和降血脂能力的影响.方法 采用灌胃高脂乳剂方法建立实验性高胆固醉血症大鼠模型,检测血清和肝脏的甘油三酯(TG)和总胆固醉(TC)含量,分析血清和肝脏的抗氧化酶活性、丙二醛(MDA)含量和总杭氧化力.结果 SOP可以有效提高高血脂大鼠血清的TG水平(P<0.0...

关 键 词:鲢鱼  寡肽  抗氧化  调节血脂

STUDY ON THE EFFECTS OF SILVER CARP OLIGOPEPTIDE ON LIPID METABOLISM AND ANTIOXIDANT ABILITY OF HYPERLIPIDEMIC RATS
DONG Shi-yuan,MENG Yan-li,ZHAO Yuan-hui,LIU Zun-ying,ZENG Ming-yong. STUDY ON THE EFFECTS OF SILVER CARP OLIGOPEPTIDE ON LIPID METABOLISM AND ANTIOXIDANT ABILITY OF HYPERLIPIDEMIC RATS[J]. Acta Nutrimenta Sinica, 2011, 33(2): 121-124
Authors:DONG Shi-yuan  MENG Yan-li  ZHAO Yuan-hui  LIU Zun-ying  ZENG Ming-yong
Abstract:Objective To investigate the effects of silver carp oligopeptide(SOP)on lipid metabolism and antioxidant ability of hyperlipidemic rats.Method The hypercholesterolemia model for the rats was established by administering orally with high fat emulsion.The contents of total cholesterol(TC),triglyceride(TG) and malondialdehyde(MDA) in serum and liver;and the total antioxidant capacity(T-AOC),superoxide dismutase(SOD) and glutathione peroxidase(GSH-Px) activities were examined.Results SOP significantly decreased TC and increased TG level(P<0.05) of serum and significantly decreased the TC and TG level of liver in hyperlipidemic rats.In the meantime,SOP significantly increased T-AOC,SOD and GSH-Px activities and decreased MDA contents of serum and liver in hyperlipidemic rats.Conclusion SOP can improve the antioxidation levels and lipid metabolism of rats with hyperlipidemia.
Keywords:silver carp  oligopeptide  blood lipid regulation  antioxidant
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