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Implementation of a mobile team to provide normothermic regional perfusion in controlled donation after circulatory death: Pilot study and first results
Authors:Marina Pérez Redondo  Sara Alcántara Carmona  Inmaculada Fernández Simón  Héctor Villanueva Fernández  Alfonso Ortega López  Cándido Pardo Rey  Jorge Duerto Álvarez  Inés Lipperheide Vallhonrat  Manuel González Romero  Daniel Ballesteros Ortega  Francisco del Río Gallegos  Juan José Rubio Muñoz
Institution:1. Department of Intensive Care Medicine, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain;2. Department of Intensive Care Medicine and Transplant Coordinator. Hospital, Universitario Clínico San Carlos, Madrid, Spain
Abstract:Normothermic regional perfusion (NRP) in controlled donation after circulatory death is becoming a popular method due to the favorable results of the grafts procured under this technique. This procedure requires experience, and, sometimes, the availability of extracorporeal membrane oxygenation (ECMO) machines to implement NRP is limited to tertiary hospitals. In order to provide support with NRP in controlled donation after circulatory death across the different hospitals of the Autonomous Community of Madrid, a mobile NRP team was created. In the first 18 months since its creation, the mobile NRP team participated in 33 procurements across nine different hospitals, representing 72% of all controlled donations after circulatory death in the Autonomous Community of Madrid. NRP was successfully performed in 29 (88%) cases, with a mean duration of 69 ± 27 minutes. A total of 39 kidneys, 12 livers, and 5 bilateral lungs were recovered and transplanted. None of the livers were discarded due to an elevation in transaminases during NRP. A mobile NRP team is a feasible option and, in our series, aided in the optimization and recovery of organs from donors after controlled circulatory death in centers where ECMO technology was not available.
Keywords:donation after circulatory death  donors and donation  extracorporeal membrane oxygenation  organ perfusion and preservation  organ procurement
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