A meissnerian neurofibroma: Case report of a rare neurofibroma variant |
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Authors: | Titilola Sode Elaine Kunzler Bianca Uzoma Martha McCollough Gregory A Hosler |
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Institution: | 1. ProPath Dermatopathology, Dallas, Texas, USA;2. Univeristy of Texas Southwestern Medical Center, Department of Dermatology, Dallas, Texas, USA;3. University of Texas Medical Branch School of Medicine, Galveston, Texas, USA;4. U.S. Dermatology Partners, Tyler, Texas, USA |
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Abstract: | Structures resembling Meissner corpuscles have been described in various nerve sheath tumors, including schwannomas and neurofibromas. When present, they are focal or scattered, and rarely a prominent feature of the lesion. Here, we report a case of a 39-year-old female who presented with an isolated lesion on her abdomen. Histopathologically, the tumor was almost exclusively composed of Meissner corpuscle-like structures (pseudo-meissnerian bodies). At a small edge of the tumor, there were features of a classic neurofibroma, with a mixture of Schwann cells, fibroblast-like cells, and interspersed mast cells. We propose the term “meissnerian neurofibroma” for this extremely rare variant of neurofibroma. |
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Keywords: | Meissner body Meissner corpuscle nerve sheath tumor neurofibroma pacinian neurofibroma pseudo-meissnerian body schwannoma tactile corpuscle |
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