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Modification of the cyclopropyl moiety of abacavir provides insight into the structure activity relationship between HLA-B*57:01 binding and T-cell activation |
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| Authors: | Paul J. Thomson Patricia T. Illing John Farrell Mohammad Alhaidari Catherine C. Bell Neil Berry Paul M. O’Neill Anthony W. Purcell Kevin B. Park Dean J. Naisbitt |
| Affiliation: | 1. MRC Centre for Drug Safety Science, Department of Molecular & Clinical Pharmacology, University of Liverpool, Liverpool, UK;2. Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Australia |
| Abstract: | |
| Keywords: | drug hypersensitivity HLA human mass spectrometry T-cells |