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Editorial comment: variables affecting the presence of mesenchymal stromal cells in the peripheral blood and their relationship with apheresis product
Authors:Guido Moll  Norman Drzeniek  Julian Kamhieh-Milz  Sven Geissler  Petra Reinke
Institution:1. BIH Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany;2. BIH Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany

Berlin-Brandenburg School for Regenerative Therapies (BSRT), Charité Universitätsmedizin Berlin, Berlin, Germany;3. Department of Transfusion Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany

Abstract:Paediatric haematology began to establish itself as a speciality in the UK just over 60 years ago. In that time, clinical trials involving all the specialist centres in the country, and based on scientific advances, have dramatically improved the outlook for children with a range of malignant and non-malignant disorders, but particularly acute leukaemia. As in many specialties, multidisciplinary teams have played a major role in delivering these advances. With these structures in place at a national level, perhaps, of all specialities, paediatric haematology is poised to benefit from the new developments in precision medicine, gene editing and immunotherapy.
Keywords:haematopoietic stem cell transplantation  granulocyte colony-stimulating factor  stem cell mobilization  mesenchymal stromal cells  blood circulation  peripheral blood  apheresis product  flow cytometry
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