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Changes in perampanel levels during de-induction: Simulations following carbamazepine discontinuation |
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| Authors: | Edgar Schuck Jim Ferry Barry Gidal Ziad Hussein |
| Affiliation: | 1. Eisai Inc., Woodcliff Lake, NJ, USA;2. School of Pharmacy, University of Wisconsin, Madison, WI, USA;3. Eisai Ltd., Hatfield, Hertfordshire, UK |
| Abstract: | |
| Keywords: | carbamazepine enzyme induction epilepsy perampanel physiologically based pharmacokinetic modeling |