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| 口服缓控释微丸的研究进展 | |
| 引用本文： | 陈婷,张倩,宋洪涛. 口服缓控释微丸的研究进展[J]. 药学实践杂志, 2011, 29(3): 169-172,192 |
| 作者姓名： | 陈婷 张倩 宋洪涛 |
| 作者单位： | 1. 南京军区福州总医院药学科,福建,福州,350025;福建医科大学福总临床医学院药学科,福建,福州,350025;福建医科大学药学院,福建,福州,350004 2. 福建医科大学药学院,福建,福州,350004 3. 南京军区福州总医院药学科,福建,福州,350025;福建医科大学福总临床医学院药学科,福建,福州,350025 |
| 摘 要： | 目的综述近年来国内外缓控释微丸的研究进展,并展望微丸制剂的发展前景。方法查阅相关文献,并将其分析、归纳。结果阐明了不同种类缓控释微丸的特点、所选用的辅料、制备工艺及微丸压片技术。结论微丸作为一种多单元释药系统,具有较多优点,随着现代制备工艺的逐渐成熟及辅料的发展,微丸成为目前缓控释制剂发展的重要方向。 |
| 关 键 词： | 微丸 辅料 包衣 压片技术 |
| 收稿时间： | 2010-09-15 |
| 修稿时间： | 2010-12-21 |
Progress of oral sustained-release and controlled-release pellets |
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| CHEN Ting,ZHANG Qian and SONG Hong-tao. Progress of oral sustained-release and controlled-release pellets[J]. The Journal of Pharmaceutical Practice, 2011, 29(3): 169-172,192 | |
| Authors: | CHEN Ting ZHANG Qian SONG Hong-tao |
| Affiliation: | Department of Pharmacy,Fuzhou General Hospitol of PLA,Fuzhou 350025,China;Department of Pharmacy,School of clinical medicine of Fuzhou General Hospital,Fujian Medical University,Fuzhou 350025,China;School of Pharmacy,Fujian Medical University,Fuzhou 350004,China;School of Pharmacy,Fujian Medical University,Fuzhou 350004,China;Department of Pharmacy,Fuzhou General Hospitol of PLA,Fuzhou 350025,China;Department of Pharmacy,School of clinical medicine of Fuzhou General Hospital,Fujian Medical University,Fuzhou 350025,China |
| Abstract: | Objective To summarize the recent advances in oral sustained/controlled release pellets in international and domestic and prospect its developing future. Methods A great quantity of references were comprehensively reviewed. Results Various kinds of information of oral sustained/controlled release pellets including the characteristic,excipients,preparation methods and squash technique were summarized. Conclusions Pellets as multiple-unit drug delivery system have many advantages.With preparation techniques and excipient materials were gradually developed,pellets would play an important part in the development of sustained/controlled release drug delivery system. |
| Keywords: | pellets excipient coating squash technique |
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