| 铅染毒对大鼠体内铜元素的影响研究 |
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| 引用本文： | 李伟,范广勤,熊华宏. 铅染毒对大鼠体内铜元素的影响研究[J]. 现代预防医学, 2006, 33(10): 1878-1879 |
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| 作者姓名： | 李伟 范广勤 熊华宏 |
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| 作者单位： | 1. 南昌大学医学院公共卫生学院,南昌,330006
2. 南昌市高新开发区卫生办 |
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| 摘 要： | 目的：探讨铅染毒后对铜元素的影响和意义。方法：将SD大白鼠随机分为对照组和不同剂量醋酸铅染毒实验组。用醋酸铅饮用水染毒大白鼠8周，在第8周末处死全部动物，取血、骨、脑、肾、卵巢及睾丸组织，测定组织中铜、血铅、骨铅含量。结果：血铅和骨铅含量随铅染毒剂量增加而升高，组间差异均有统计学意义（P〈0．05）。骨、肾组织中的铜含量降低，组间差异均有统计学意义（P〈0．05）。脑组织中的铜含量升高，组间差异均有统计学意义（P〈0．05）。结论：铅染毒对大鼠体内组织中铜的含量有影响。
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| 关 键 词： | 铜 铅 染毒 影响 |
| 文章编号： | 1003-8507（2006）10-1878-02 |
| 收稿时间： | 2005-10-24 |
| 修稿时间： | 2005-10-24 |
STUDY ON EFFECTS OF EXPOSURE TO LEAD ON COPPER IN RATS. |
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| LI Wei,FAN Guang-qin,XIONG Hua-hong. STUDY ON EFFECTS OF EXPOSURE TO LEAD ON COPPER IN RATS.[J]. Modern Preventive Medicine, 2006, 33(10): 1878-1879 |
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| Authors: | LI Wei FAN Guang-qin XIONG Hua-hong |
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| Affiliation: | School of Public Health, Medical College, Nanchang University, Nanchang, 330006. |
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| Abstract: | Objective:To study the effects of exposure to lead on copper.Methods:SD rats were randomly divided into control group and several experimental groups which exposed to different doses of lead acetate.The rats were exposed to lead acetate through intragastric administration for 8 weeks.The blood,bone,brain.kidney,ovaries and testis of all rats were extracted in the end of the 8th week.The contents of copper in these tissues and lead in blood and bone were measured.Results:The contents of lead in blood and bone increased with the increase of exposure dose to lead and the differences among above groups were significant(P<0.05).The contents of copper in bone and kidney decreased but in brain increased,the differences among above groups were significant(P<0.05).Conclusion:Exposure to lead had effects on contents of copper in tissues of rats. |
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| Keywords: | Copper Lead |
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