| 糖尿病合并急性心肌梗死和缺血性脑梗塞患者血浆纤溶成分与血脂水平的变化 |
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| 引用本文： | 席刚,侯东哲,刘芳,陆彤,李毅,张春时. 糖尿病合并急性心肌梗死和缺血性脑梗塞患者血浆纤溶成分与血脂水平的变化[J]. 中国慢性病预防与控制, 2002, 10(1): 8-9 |
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| 作者姓名： | 席刚 侯东哲 刘芳 陆彤 李毅 张春时 |
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| 作者单位： | 天津市环湖医院,内科,天津,300060 |
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| 摘 要： | 目的探讨糖尿病患者并发急性心肌梗死和缺血性脑梗塞时血糖、血脂、组织型纤溶酶原激活剂 (t- PA)及其抑制物 (PAI)的水平变化及临床意义。方法该院内科收治的 98例糖尿病合并急性心肌梗死和缺血性脑梗塞患者为观察组 ,与 40例健康对照组进行比较。观察指标为血 t- PA、PAI、血脂、血糖。结果观察组的血糖 (FBG)、胆固醇 (TC)、甘油三酯 (TG)及 PAI含量明显高于对照组 ,而高密度脂蛋白 (HDL- C)、t- PA含量明显低于对照组 (P均 <0 .0 1)。结论糖尿病合并急性心肌梗死和缺血性脑梗塞患者存在血糖、血脂及血纤溶功能异常。纤溶成分的变化可能与血栓形成密切相关
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| 关 键 词： | 糖尿病 急性心肌梗死 缺血性脑梗塞 组织型纤溶酶原激活剂 纤溶酶原激活抑制剂 |
| 文章编号： | 1004-6194(2002)01-0008-02 |
| 修稿时间： | 2001-07-06 |
Variation of Plasma t-PA,PAI and Lipid Levels in Patients of Diabetes Complicated with Acute Myocardial Infarction and Ischemic Cerebral Infarction |
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| XI Gang,et al.. Variation of Plasma t-PA,PAI and Lipid Levels in Patients of Diabetes Complicated with Acute Myocardial Infarction and Ischemic Cerebral Infarction[J]. Chinese Journal of Prevention and Control of Chronic Non-Communicable Diseases, 2002, 10(1): 8-9 |
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| Authors: | XI Gang et al. |
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| Affiliation: | XI Gang,et al.Department of Internal Medicine,Tianjin Huanhu Hospital,Tianjin 300060,P.R.China |
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| Abstract: | Objective To investigate the levels of plasma tissue type plasminogen activator(t PA),plasminogen activator inhibitor (PAI) and lipids in patients of diabetes complicated with acute myocardial infarction and ischemic cerebral infarction and clinical significance of these indexes.Methods In our ward there were 98 patients of diabetes complicated with acute myocardial infarction and ischemic cerebral infarction in the observed group and there were 40 health in the control group.Observed indices were plasma t PA,PAI,lipids and blood sugar.Results Contents of fasting blood glucose (FBG),total cholesterol (TG),triglyceride (TG) and plasminogen activator inhibitor (PAI) in observed group were significantly higher than that in control group ( P <0 01).Contents of HDL C and t PA in observed brorp were significantly lower than that in control group ( P <0 01).Conclusion There were abnormal lipids and fibrinolytic activities in patients of diabetes complicated with acute myocardial infarction and ischemic cerebral infarction.Variation of fibrinolytic components is possible closely related to thrombosis. |
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| Keywords: | Diabetes Acute myocardial infarcion Ischemic cerebral infarction Tissue type plasminogen activator (t PA) Plasminogen activator inhibitor (PAI) |
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