新生儿缺氧缺血性脑病围产期危险因素分析

目的分析围产期各种危险因素对新生儿缺氧缺血性脑病(HIE)发病的影响,为其预防提供依据。方法对150例HIE患儿母妊娠期病史及分娩情况进行回顾性分析;随机抽取146例同期出生无HIE新生儿作对照,分析HIE发病危险因素。结果两组中妊高征、胆汁淤积、脐带异常、胎儿宫内窘迫及新生儿窒息存在统计学差异,为HIE危险因素。结论加强围产期保健,提高产科质量,及时处理妊娠并发症,及早发现和处理胎儿宫内窘迫,避免新生儿窒息,对预防和减少新生儿HIE具有重要意义。

Analysis on perinatal risk factors of hypoxic ischemic encephalopathy

Objective:To analyze the correlation between perinatal factors and neonatal hypoxic ischemic encephalopathy (HIE), and provide basis consideration for preventing HIE.Methods:150 neonates diagnosed as HIE, with control of 146 cases having no HIE were retrospectively compared to analyze the risk factors of HIE.Results:There was a significant difference of perinatal factors in two groups. HIE was significantly associated with pregnancy induced hypertension, intrahepatic cholestasis of pregnancy, umbilical cord abnormalities, fetal intrauterine distress and neonatal asphyxia.Conclusion:Promoting the health care of perinatal peroid, improving the quality of obstetrics, dealing with pregnancy complications in time, early finding and dealing with fetal intrauterine distress, avoiding neonatal asphyxis are important factors contributed to prevent and lower the incidence rate of HIE.