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预防心脏手术中使用鱼精蛋白不良反应的临床观察
引用本文:庞宏宣,林高翔.预防心脏手术中使用鱼精蛋白不良反应的临床观察[J].华夏医学,2006,19(6):1080-1082.
作者姓名:庞宏宣  林高翔
作者单位:桂林医学院附属医院麻醉科,广西,桂林,541001;桂林医学院附属医院麻醉科,广西,桂林,541001
摘    要:目的探讨心脏手术中使用鱼精蛋白出现不良反应的预防与治疗方法。方法将200例使用鱼精蛋白的病例随机分成两组,实验组使用鱼精蛋白时采取多种预防措施,对照组不采取预防措施,观察两组不良反应的发生率和不良反应的程度。对出现不良反应的病例采取积极的治疗措施。结果两组都有不良反应发生,不良反应种类及程度相似,但实验组与对照组相比不良反应的发生率低(P<0.01),两组出现不良反应后及时治疗效果好。结论心脏手术中使用鱼精蛋白的不良反应难以避免,但采取多种有效的防治措施能减少不良反应的发生,避免更严重的并发症。

关 键 词:鱼精蛋白  不良反应  心脏手术
文章编号:1008-2409(2006)06-1080-03
修稿时间:2006年4月17日

The prevention and treatment adverse reactions of the use of protamine during cardiac surgical operation
PANG Hong-xuan,LIN Gao-xiang.The prevention and treatment adverse reactions of the use of protamine during cardiac surgical operation[J].Acta Medicinae Sinica,2006,19(6):1080-1082.
Authors:PANG Hong-xuan  LIN Gao-xiang
Abstract:Objective: To explore the prevention and treatment reactions of the use of protamine during open heart operation. Methods:200 patients using protamine were randomly divided into two groups. Experimental group was used variety prevention methods.The control group was not taken preventive measures. Results: Two group all appeared reactions of the use of protamine. But experimental group showed the low incidence of adverse reaction (P<0.01)compared with control group.The active treatment measures could improve the situation of cases with adverse reactions . Conclusion:It is difficult to avoid the adverse reactions when using protamine in heart surgery.But a variety of effective prevention and control measures can be used to reduce the occurrence of adverse reactions, to avoid more serious complications.
Keywords:Protamine  side reaction  cardiac surgical operation
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