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Phosphoinositide metabolism in endothelial cells of human umbilical vein effected byY. pestis toxin
Authors:T. D. Cherkasova  V. A. Yurkiv  V. I. Pokrovskii
Affiliation:(1) Central Research Institute of Epidemiology, Moscow
Abstract:Histamine stimulates the metabolism of inositol phosphates and raises the level of prostacycline in endothelial cells. The activatory effect of histamine markedly decreases when incubation is performed in the presence of PT, whereas the baseline level of phosphoinositide metabolites does not change in endothelial cells. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N o 2, pp. 153–155, February, 1994
Keywords:plague toxin    endothelium of human umbilical vein    phosphoinositide metabolism
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