无花果叶提取物抗新城疫病毒的实验研究

目的 为研究无花果叶乙醇提取物和无花果叶水提取物体外抗新城疫病毒（NDV）作用。方法 采用组织细胞培养技术，充分利用无花果叶提取物中的有效成分，在人上皮样癌（Hep-2）细胞株、地鼠肾（BHK21）细胞株和鸡胚成纤维细胞（CEF）上研究其抗新城疫病毒的作用。结果 无花果叶提取物在体外对NDV具有明显的抑制和杀灭作用，药物的最小有效浓度（MIC）N0．5mg／ml，无花果叶乙醇提取物和无花果叶水提取物最大无毒浓度（TDO）分别为550mg／ml和50mg／ml。治疗指数（TI）分别为1100和100。结论 无花果叶提取物对NDV具有抑制和杀灭的特异性。在医药食品领域的应用具有广阔的前景。

Anti-NDV Effect of extract from ficus carica leave

Tissue cell culturing technology was adopted to study the anti-NDV effect of the extract from the ficus carica leaves, the effective ingredient was extracted from the leaves of Ficus carica, and the anti-virus effect was observed on Hep-2, BHK21 and CEF cells. It was found that the extract of Ficus carica leaves showed remarkable inhibitory and killing effects on the Newcastle disease virus. The MTC was 0.5 mg/ml, and the TDO of extract of leaves of Ficus carica with ethanol and with water was 55 mg/ml and 50mg/ml respectively. The experimental TI was 1100 and 100 respectively. It concluded that the extract from Ficus carica leave has effect on NDV and it provide the wide application future in the field of medicine, food and drug.