19-oxygenated ent-kaurane diterpenoids from Isodon pharicus |
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Authors: | Zhao Yong Pu Jian-Xin Huang Sheng-Xiong Ding Li-Sheng Li Li-Mei Li Xian Yang Li-Bin Xiao Wei-Lie Wu Ying-Li Chen Guo-Qiang Sun Han-Dong |
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Affiliation: | State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People's Republic of China. |
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Abstract: | Eight new 19-oxygenated ENT-kaurane diterpenoids were isolated from the aerial parts of Isodon pharicus. Their structures were determined by means of extensive spectroscopic techniques including interpretation of 1D and 2D?NMR spectra. Selected compounds were evaluated for their cytotoxicity against NB4, A549, PC-3, MCF-7, and SH-SY5Y cell lines. |
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