右美托咪定在腹部手术硬膜外麻醉中的辅助效果研究

目的 探讨右美托咪定在腹部手术硬膜外麻醉中的辅助效果。方法 以本院106例腹部手术患者为研究对象,观察组（53例）静脉注射右美托咪定辅助硬膜外麻醉,对照组（53例）静脉注射生理盐水,观察和比较两组的辅助治疗效果。结果 观察组的内脏牵拉反应发生率为15.09%,寒战发生率为9.43%,对照组的内脏牵拉反应发生率为41.51%,寒战发生率为30.19%,两组比较差异有统计学意义（P〈0.05）。观察组给药15 min后心率、警觉/镇静观察评分明显低于对照组（P〈0.05）。观察组不良反应发生率为13.21%,对照组不良反应发生率为9.43%,差异有统计学意义（P〈0.05）。结论 右美托咪定在腹部手术硬膜外麻醉中的辅助效果明显,值得临床推广应用。

Auxiliary effect research of dexmedetomidine in epidural anesthesia of operation on abdominal region

Objective To investigate the auxiliary effect of dexmedetomidine in epidural anesthesia of operation on abdominal region. Methods 106 cases of patients with abdominal surgery were selected as research objects in our hospital. Intravenous dexmedetomidine given epidural anesthesia was taken by observation gtoup（53 cases）,normal saline was used in control group（53 cases）.The auxiliary effect of both groups was observed and compared. Results Incidence rate of vis- ceral traction reaction and chili in observation group was 15.09% and 9.43% respectively,incidence rate of visceral traction reaction and chili in control group was 41.51% and 30.19% respectively,with statistical difference（P〈0.05）.Heart rate and alertness/sedation observed score after 15-min in observation group was significantly lower than that in control group respectively（P〈0.05）.Incidence rate of adverse reaction in observation group was 13.21%,incidence rate of adverse reaction in control group was 9.43%,with statistical difference（P〈0.05）. Conclusion Dexmedetomidine has a significant auxil- iary effect in epidural anesthesia of operation on abdominal region,which is worthy of clinical promotion and application.