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Over-expression of Nrf2 diminishes ethanol-induced oxidative stress and apoptosis in neural crest cells by inducing an antioxidant response
Institution:1. Department of Oncology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA;2. Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, MD 20852, USA;3. Graduate Program in Cellular and Molecular Medicine, Johns Hopkins, Baltimore, MD 21231, USA;4. Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 2120, USA;5. Department of Radiation Oncology and Stanford Cancer Institute, Stanford University, Palo Alto, CA, USA;1. ICU Center, The Second Xiangya Hospital, Central South University, No. 139 Renmin Middle Road, Furong, Changsha 410011, Hunan, China;2. Department of Respiratory, Anhui Provincial Hospital, No. 17 Luyang Road, Hefei 230011, Anhui, China;3. Department of Pediatrics, The Second Xiangya Hospital, Central South University, No. 139 Renmin Middle Road, Furong, Changsha 410011, Hunan, China;4. Department of Urology, The Second Xiangya Hospital, Central South University, No. 139 Renmin Middle Road, Furong, Changsha 410011, Hunan, China;1. Department of Translational Bioscience, Human Health Therapeutics, National Research Council Canada, 1200 Montreal Road, Ottawa, Ontario, Canada K1A 0R6;2. Université de Nice Sophia Antipolis, IPMC, Sophia Antipolis, F-06560, France;3. CNRS, IPMC, Sophia Antipolis, F-06560, France
Abstract:
Keywords:Nrf2  Ethanol  Apoptosis  Neural crest cells  Antioxidant
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